KIT anticorps

N° du produit ABIN319615

Cet anticorps Rat Monoclonal détecte spécifiquement KIT dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour KIT anticorps (ABIN319615)

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp KIT est non-conjugé

Application: Flow Cytometry (FACS)

Clone: 2B8

Détail du produit anti-KIT anticorps

Specificité: This antibody reacts with CD117 also known as Kit or c-kit receptor. Clone 2B8 recognises an epitope within the extracellular region of CD117.

Purification: Affinity Chromatography on Protein G.

Immunogène: IL-3 dependent mast cells. Spleen cells from immunised Wistar rats were fused with cells of the Fox-NY mouse myeloma cell line.

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry: Use 10 μL of 1/50-1/200 diluted antibody to label 10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur KIT

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Autre désignation: CD117 / C-Kit

Sujet: CD117 is the receptor of the steel factor (Stem Cell Factor). C-kit receptor is expressed on 5-10 % of total adult bone marrow cells including multipotent hematopoietic cells.Synonyms: KIT, Mast/stem cell growth factor receptor, Proto-Oncogene Tyrosine-Protein Kinase, SCFR

ID gène: 16590

NCBI Accession: NP_066922

UniProt: P05532

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity